Rivotril (Clonazepam) Uses, Dosage, Side Effects
What is Rivotril 2 mg used for?
Clonazepam Rivotril is a benzodiazepine derivative with several pharmacological properties characteristic of the benzodiazepine class. In humans, clonazepam can suppress spike-and-wave discharges associated with absence seizures (petit mal) and reduce the frequency, amplitude, duration, and spread of discharges associated with minor motor seizures. In addition, clonazepam shares several pharmacodynamic properties with other benzodiazepines, including anticonvulsant, sedative, muscle-relaxing, and anxiolytic effects.
| Attribute | Details |
|---|---|
| Trade Name | Rivotril |
| Availability | Prescription only |
| Generic | Clonazepam |
| Clonazepam Other Names | Clonazepam, Clonazepamum |
| Related Drugs | gabapentin, sertraline, fluoxetine, alprazolam, Zoloft, Xanax, lamotrigine, diazepam, Prozac, pregabalin |
| Weight | 0.25%w/v, 2mg, 0.5mg, , 2.5mg/ml |
| Type | Tablet, Drops, Solution/ Drops, Oral |
| Formula | C15H10ClN3O3 |
| Weight | Average: 315.711 Monoisotopic: 315.041068908 |
| Protein binding | The recorded plasma protein binding of clonazepam ranges between 82–86% . |
| Groups | Approved, Illicit |
| Therapeutic Class | Adjunct anti-epileptic drugs, Benzodiazepine hypnotics |
| Manufacturer | Abbott Healthcare Pvt Ltd, Roche Pakistan Ltd,, Roche Bangladesh Limited |
| Available Country | India, Pakistan, Bangladesh, Canada, Australia, Saudi Arabia, United States, Portugal, Switzerland |
| Last Updated: | January 7, 2025, at 1:49 am |
What is Rivotril 2 mg used for?
Rivotril (clonazepam) may be used as part of treatment for certain seizure disorders and, in some cases, other neurological or psychiatric conditions. Depending on the condition, its use may be approved, specialist-directed, or considered off-label. Conditions associated with clonazepam treatment may include:
- Akinetic seizures
- Myoclonic seizures
- Refractory absence seizures
- Lennox-Gastaut syndrome (LGS)
- Panic disorder
- Restless legs syndrome (RLS)
- Rapid eye movement (REM) sleep behavior disorder
- Essential tremor
- Tardive dyskinesia (TD)
- Gilles de la Tourette syndrome
- Burning mouth syndrome
- Acute manic episodes
- Mixed manic-depressive episodes
The appropriate use of Rivotril depends on the individual’s diagnosis, medical history, other medications, and clinical response. Clonazepam is a benzodiazepine medicine, so treatment should be used only under appropriate medical supervision.
How long does it take for Rivotril to work

Gamma-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the human body. When GABA binds to GABA-A receptors at neuron synapses, chloride ions move across neuron cell membranes through ion channels within these receptors. As a result, sufficient chloride ions can hyperpolarize the local neuron membrane, making action potentials less likely to fire. Therefore, GABA reduces neuronal excitation and helps regulate excessive activity in the central nervous system.
Maximum dose of clonazepam in a day
Clonazepam dosage child
Tablet:
Health Conditions
Initial dose: 0.01 – 0.03 mg/kg/day. Up to 1 year: 0.25 mg daily in divided dose, not to exceed 0.05 mg/kg/days increase gradually to 0.5 – 1 mg.
Increment dose: not more than 0.25 – 0.5 mg 1 – 5 years: 0.25 mg daily in divided dose, at intervals of 3 days increase to 1 – 3 mg.
Maintenance dose: 0.1 – 0.2 mg/kg/day. 5 – 12 years: 0.5 mg daily in divided dose,
Dosing interval: b.i.d. / t.i.d. increase to 3 – 6 mg.
Clonazepam dosage adults
Initial dose: 1 mg daily in divided dose (Elderly 0.5 mg), not to exceed 1.5 mg/day
Increment dose: 0.5 – 1 mg at intervals of 3 days
Maintenance dose: 4 – 8 mg/day
Maximum dose: 20 mg/day should be administered with caution
Dosing interval: b.i.d. / t.i.d.
Initial dose should be low and increased gradually to a maintenance dose that controls seizures without toxic effects. During discontinuation, the dose should be tapered.
Clonazepam injection dosage
Clonazepam Rivotril may be administered intravenously in certain emergency clinical situations. The appropriate dose, administration rate, and total amount depend on the patient’s age, condition, and clinical response. Healthcare professionals should administer intravenous clonazepam slowly or by appropriate infusion and monitor the patient closely throughout treatment.
How long does Rivotril take to work
How Long Does It Take to Work? see here Rivotril
Drugs & Medications
Side Effects of Clonazepam Rivotril
Tablet:
The most frequently reported side effects of clonazepam are associated with central nervous system depression. These may include drowsiness, fatigue, dizziness, muscle hypotonia, coordination problems, hypersalivation in infants, paradoxical aggression, irritability, and mental changes.
Injection:
FAQ
What is Rivotril used for?
Rivotril is a medication used to prevent and treat seizures, panic disorder, anxiety, and the movement disorder known as akathisia. It’s used to control seizures or fits due to epilepsy, involuntary muscle spasms and sometimes restless legs syndrome.
Sleep Disorders
How safe is Rivotril?
Rivotril is a safe and effective medication when used as directed.
How does Rivotril work?
Rivotril works by increasing levels of a calming chemical in your brain.
What are the common side effects of Rivotril?
Common side effects of Rivotril include:
- drowsiness
- dizziness
- unsteadiness
- problems with coordination
- difficulty thinking or remembering
- increased saliva
- muscle or joint pain
- frequent urination
- blurred vision
- changes in sex drive or ability
Is Rivotril safe during pregnancy?
No, because taking Rivotril during pregnancy is not recommended because it can create risks for the unborn baby.
Is Rivotril safe during breastfeeding?
Rivotril gets into the breast milk in small amounts. Because it can cause sedation and levels might build up in the infant’s body, other medications may be preferred while breastfeeding a newborn or an exclusively breastfed infant.
Can Rivotril cause weight loss?
Some people experience unintended weight loss on this bran, while other people find it more difficult to exercise when taking Rivotril.
When should be taken of Rivotril?
It usually is taken one to three times a day with or without food. Take Rivotril at around the same time everyday.
How long does Rivotril take to work?
Rivotril takes approximately 20-60 minutes to start working. The peak effects of Rivotril are reached in 1-4 hours.
Is Rivotril fast acting?
Rivotril is a fast-acting benzodiazepine. It relaxes your emotions and muscles by affecting chemicals in the brain.
Is Rivotril the best for anxiety?
Rivotril acts quickly on social anxiety symptoms, but the other potential benefits of the medication can take longer to appear.
Can I take Rivotril for a long time?
Rivotril is not generally recommended for long-term use because it is known to be a habit-forming substance. Over time, the patient’s body tends to build a tolerance to Rivotril.
What happens if I take Rivotril every day?
Rivotril is a safe and effective medication when used as directed. Rivotril may produce emotional and/or physical dependence (addiction) even when used as recommended. Physical dependence may develop after 2 or more weeks of daily use.
Can I take Rivotril for a long time?
Rivotril is not generally recommended for long-term use because it is known to be a habit-forming substance. Over time, the patient’s body tends to build a tolerance to Rivotril.
Who should not take Rivotril?
You should not take Rivotril if you have liver problems, severe liver disease, sleep apnea, susceptible to breathing fluid into lungs.
What happens if I miss a dose?
Take Rivotril as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose of Rivotril?
Seek emergency medical attention or contact a poison control service if a Rivotril overdose occurs. An overdose can become life-threatening, especially when combined with alcohol, opioids, or other medicines that cause drowsiness or slow breathing. Symptoms may include extreme drowsiness, confusion, muscle weakness, difficulty breathing, or loss of consciousness.
What happens when Rivotril stops working?
Stopping Rivotril abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, tremor, dizziness, blood pressure changes, rapid heart rate, and seizures.
Can Rivotril cause heart problems?
They slow down heart and breath rate. If you take too much of a Rivotril , you risk slowing your heart rate to damaging or fatal levels.
Can Rivotril cause liver or kidney damage?
No cases of acute liver failure or chronic liver injury due to Rivotril have been described. There is no information about cross-reactivity with other benzodiazepines, but some degree of cross sensitivity should be assumed.
Drugs & Medications
Can Rivotril effect my fertility?
There’s no evidence that Rivotril will affect fertility in either men or women. If you’re trying to get pregnant, or you’re having problems getting pregnant while on Rivotril, speak to a doctor.